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Nitrogenous bases covalently linked to a sugar with and without phosphate groups; used for synthesis, cell signaling, and as cofactors in enzymatic reactions; includes pyrimidine, purine, pyridine, flavin, pyrrolopyrimidine, and triazole varieties.
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N6-Benzyladenosine is an adenosine receptor agonist with cytoactive activity. It arrests the cell cycle at the G0/G1 phase and induces cell apoptosis. It also inhibits *T. gondii* adenosine kinase and glioma, making it suitable for various research applications.
Adenosine receptor agonist
Induces cell apoptosis
Arrests cell cycle at G0/G1 phase
Inhibits *T. gondii* adenosine kinase
Exerts anti-glioma activity
Suppresses clonogenic activity and growth of various neoplastic cells
Potent inducer of apoptosis with caspase-3 and caspase-9 activation
Induces chromatin condensation, apoptotic body formation, and DNA cleavage
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Also available in 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 3'-Deoxyguanosine is a ligand that can be complexed with enzymes such as purine nucleoside phosphorylase and receptors. purity: 98%
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2′-Deoxyguanosine 5′-monophosphate-13C10,15N5 dilithium is an isotopically labeled nucleotide provided as the dilithium salt. It is intended for use as a tracer and internal standard in quantitative analyses by NMR, GC-MS, and LC-MS, and is supplied in small, pre-weighed pack sizes suitable for preparing standard solutions.
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2'-Deoxyadenosine 5'-triphosphate disodium is a nucleotide with important biological activities. It plays a key role in DNA synthesis and reverse transcription and is widely utilized in in vitro reactions in molecular biology research.
Serves as a substrate for various polymerases
Supports DNA synthesis
Supports reverse transcription
Suitable for in vitro reactions in molecular biology research
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2'-Deoxyguanosine 5'-monophosphate (dGMP) disodium hydrate is an oxidizable target of pterin (PT) used to evaluate the photosensitizing properties of biopterins. Pterin induces a photosensitive reaction of dGMP under UV-A radiation, leading to DNA damage via two primary mechanisms: electron transfer (type I) and singlet molecular oxygen production (type II).
Oxidizable target of pterin (PT).
Evaluates photosensitizing properties of biopterins.
Induces DNA damage under UV-A radiation.
Functions through Type I (electron transfer) and Type II (singlet molecular oxygen production) mechanisms.
Relevant to cell cycle and DNA damage studies.
Involved in DNA/RNA synthesis research.
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6-Thio-2'-Deoxyguanosine is a nucleoside analogue that can be incorporated into de novo-synthesized telomeres by telomerase.
Nucleoside analogue
Can be incorporated into de novo-synthesized telomeres by telomerase
Rapid cell death for the vast majority of cancer cell lines tested with IC50s of between 0.7-2.9 μM (in vitro)
Causes a decrease of the tumor growth rate in A549 lung cancer cell-based mouse xenograft studies, superior to that observed with 6-thioguanine treatment (in vivo)
Increases telomere dysfunction in tumor cells in vivo
Appearance: Solid
Color: White to yellow
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CA15-3 (Carcinoma antigen 15-3) is also known as MUC 1 antigen It is a membrane-anchored mucin-type glycoprotein present in malignant cells It is used as tumor marker to monitor breast cancer treatment and disease recurrence
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CA15-3 (Carcinoma antigen 15-3) is also known as MUC 1 antigen It is a membrane-anchored mucin-type glycoprotein present in malignant cells It is used as tumor marker to monitor breast cancer treatment and disease recurrence
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Also available in 10 mg, 25 mg, 50 mg and bulk. Please contact Fisher for quotes. 5'-Amino-5'-deoxyadenosine (NH2dAdo) is an adenosine kinase inhibitor targeting malignant tumors of the inert lymphatic system with antitumor and anticancer effects. Its mechanism is mediated by the inhibition of DNA synthesis and induction of apoptosis. Purity 95.55%
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